Cerebrasol has extensive experience in delivering first class preclinical translational research into the study, treatment and prevention of neurodegenerative disorders, particularly around amyloid based animal models of Alzheimer’s disease.
Our track record is demonstrated in our manuscript publications and our key strength is in developing precisely tailored research packages to target out client’s needs. Whether it is in vitro or in vivo electrophysiological approaches, whole animal behavior or molecular biology techniques, our research teams will provide expert consultancy in putting together the study proposal you require, and our investigators will then rapidly deliver data of the highest quality to drive forward your research programs.
|Disease Areas||Behavioural Tests||Electrophysiological Assays|
In vivo: single cells – extra and intracellular recording; iontophoretic, central and parenteral drug administration
Local field potentials – spontaneous and evoked, including LTP/LTD
Peripheral nerves – compound and single fibre
Telemetric and multi-electrode recording
In vitro: whole-cell patch-clamp recordings from brain slices (current/voltage/blind/visualised)
Local field potentials – spontaneous and evoked extracellular recordings from brain slices, including LTP/LTD and multi-electrode recording (MEA)
Ion channel pharmacology – state-dependency, kinetics, and site of action using cultured and primary dissociated neurones, cell lines